The Egyptian Journal of Internal Medicine

CASE REPORT
Year
: 2015  |  Volume : 27  |  Issue : 1  |  Page : 40--41

Esophageal squamous papilloma


Seham M Seif1, Ahmed Y Altonbary1, Wagdi F Elkashef2,  
1 Department of Hepatology and Gastroenterology, Mansoura Specialized Medical Hospital, Mansoura, Egypt
2 Department of Pathology, Mansoura Faculty of Medicine, Mansoura, Egypt

Correspondence Address:
Seham M Seif
Mansoura Faculty of Medicine, Mansoura 35516
Egypt

Abstract

Squamous papilloma of the esophagus is a rare benign tumor with less than 200 cases reported in the literature. The etiology and pathogenesis appear to be related to an inflammatory-reparatory type, such as chronic gastroesophageal reflux, esophagitis, trauma, chemical irritants, and viruses. We present the case of a young female patient with esophageal squamous papilloma discovered accidently during screening upper gastrointestinal endoscopy.



How to cite this article:
Seif SM, Altonbary AY, Elkashef WF. Esophageal squamous papilloma.Egypt J Intern Med 2015;27:40-41


How to cite this URL:
Seif SM, Altonbary AY, Elkashef WF. Esophageal squamous papilloma. Egypt J Intern Med [serial online] 2015 [cited 2024 Mar 29 ];27:40-41
Available from: http://www.esim.eg.net/text.asp?2015/27/1/40/155858


Full Text

 Introduction



Squamous papilloma of the esophagus is a rare benign tumor with less than 200 cases reported in the literature [1]. The prevalence of endoscopically diagnosed papilloma of the esophagus has been reported in only a few series and varies from 0.01 to 0.43% [2], and only seven squamous papillomas of the esophagus were recognized in 52 148 autopsies (0.013%) reported up to 1968 [3]. In addition, a case of squamous cell papillomatosis of the esophagus has been described in a patient following placement of a self-expanding metal stent [4].

 Case report



A 46-year-old women presented to our unit for screening upper gastrointestinal endoscopy before interferon therapy. The patient had chronic hepatitis C with mild splenomegaly. The endoscopy revealed a diminutive polypoid lesion in the upper third of the esophagus [Figure 1], which was removed with biopsy forceps [Figure 2]. Histological examination of the specimens was compatible with esophageal squamous papilloma with no evidence of viral inclusions [Figure 3] and [Figure 4].{Figure 1}{Figure 2}{Figure 3}{Figure 4}

 Discussion



Esophageal squamous papilloma is an uncommon benign squamous epithelial polypoid tumor and is usually identified as a solitary lesion of the lower esophagus [5]. The etiology and pathogenesis of esophageal squamous papilloma appear to be related to an inflammatory-reparatory type, such as chronic gastroesophageal reflux, esophagitis, trauma, chemical irritants, and viruses [6]. Their malignant potential is still unclear, and it has been proposed that human papillomavirus plays an etiopathogenic role; however, human papillomavirus is not consistently identified [7]. It occurs in patients across a wide age range, mostly in adults aged between 18 and 80 years, with an average of 50 years at the time of diagnosis [6]. Generally, a papilloma appears as a single, round, mulberry-like or dome-shaped elevated solid formation that is well-distinguished from the surrounding tissue. Some authors have reported multiple lesions, but only a few cases of esophageal papillomatosis have been reported [8],[9]. Follow-up is still rather insufficient in the literature. Thirty-five patients were followed up from 2 weeks to a maximum of 4 years. In two of them, the papilloma gradually disappeared and reached complete regression without special treatment. Two other papillomas had grown in diameter during the period of 6 months and 3 years. Three lesions recurred after 2, 6 months, and 1 year from endoscopic removal [10].

 Acknowledgements



Conflicts of interest

There are no conflicts of interest.

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