AU - Hassan, Auwal AU - Danazumi, Musa AU - Ishaku, Cornelius AU - Yakasai, Abdulsalam TI - Short-Interval periodic transcranial direct current stimulations may induce long-term remission of symptoms in a patient with poststroke depression PT - CASE DP - 2017 Jan 1 TA - The Egyptian Journal of Internal Medicine PG - 59-63 VI - 29 IP - 2 4099- http://www.esim.eg.net/article.asp?issn=1110-7782;year=2017;volume=29;issue=2;spage=59;epage=63;aulast=Hassan;type=0 4100- http://www.esim.eg.net/article.asp?issn=1110-7782;year=2017;volume=29;issue=2;spage=59;epage=63;aulast=Hassan AB - Transcranial direct current stimulation (tDCS) has been shown to be effective in the management of patients with poststroke depression (PSD) but with a high relapse rate. We present a report of a patient with PSD who had long-term mood improvement upon receiving periodic tDCS sessions with short inter-session intervals following a relapse of symptoms at 3 weeks after improvement due to stimulations with long inter-sessions intervals. A 60-year-old patient presented with moderate PSD, having a Beck Depression Inventory (BDI) score of 25. She received anodal tDCS to the left dorsolateral prefrontal cortex using two different application protocols. Initially, a stimulation session of 2 mA intensity for 20 min was given every working day for 2 weeks. After 3 weeks, she then received seven sessions of periodic stimulations of 2 mA intensity for 13 min each with 20 min inter-sessions interval. BDI score was taken before the intervention, immediately after, and at 3 weeks and 6 months postintervention. Immediately following the last session of the initial protocol of stimulation, the BDI score reduced from 25 to 7. However, the symptoms relapsed at 3 weeks postintervention to the initial BDI score of 25. There was no change in the BDI score immediately after follow-up with short interval periodic stimulations. Nevertheless, the BDI score improved to 18 at 3 weeks and later to 7 at 6 months postintervention. Series of periodic tDCS with short-intersession intervals may be more effective in inducing long-term mood improvement in patients with PSD.